Myxochelin A is a microbial metabolite that has been found inA. disciformisand has diverse biological activities.1It is active against Gram-positive bacteria, includingB. cereus,S. aureus, andM. luteus, but not Gram-negative bacteria or fungi in an agar diffusion assay when used at a concentration of 80 ug/disc. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity with an IC50value of 1.9 uM for the recombinant human enzyme.2It is cytotoxic to 26-L5 colon cancer cells when used at a concentration of 3 ug/ml.3