Migrastatin

Mfr.No.	T35616
Description	Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinic acetylcholine receptors (Kis = >200, 200, 31, 43, and >200 uM, respectively) and inhibits calcium mobilization induced by carbamoylcholine in SK-N-SH cells (IC50= 28 uM), as well as in primary rat bladder smooth muscle cells.1Migrastatin inhibits the migration of EC17 esophageal cancer cells in a wound healing assay (IC50= 10 ug/ml) and 4T1 mouse mammary carcinoma cells in a chamber cell migration assay (IC50= 29 uM).2It enhances cytotoxicity induced by vinblastine in vincristine-resistant P388/VCR cells.3
Molecular Formula	C27H39NO7
Signaling Pathways	Others
Smiles	(H)(C)1(OC(=O)C=C/CCC=C/(CH)(OC)(CH)(O)(CH)(C)C=C1/C)(CH)(C)C(=O)CCCC1CC(=O)NC(=O)C1 \|c:5,9,t:18\|
Cas Number	314245-65-3
Molecular Weight	489.609
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20425027	T35616	1 mg	$1890		Add to Cart