EW-7195

Mfr.No.	T38752
Description	EW-7195 is a selective and potent inhibitor of ALK5 (TGFbetaR1) with an IC50 value of 4.83 nM.EW-7195 has an affinity for ALK5 that is more than 300-fold higher than that of p38alpha.EW-7195 has an inhibitory effect on TGF-beta1-induced Smad signaling, epithelial mesenchymal transition (EMT), and breast cancer metastasis to the lungs.
Molecular Formula	C23H18N8
Signaling Pathways	Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors
Smiles	NCC1=CC=CC(=C1)NCC2=NC(C3=NC(=CC=C3)C)=C(N2)C=4C=CC5=NC=NN5C4
Cas Number	1352609-28-9
Molecular Weight	406.44
Target	TGF-beta/Smad, ALK

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SKU	Supplier No.	Size	Your price
BHB20427516	T38752	1 mL	$363	Add to Cart
BHB20427516	T38752	1 mg	$133	Add to Cart
BHB20427516	T38752	2 mg	$196	Add to Cart
BHB20427516	T38752	5 mg	$328	Add to Cart
BHB20427516	T38752	10 mg	$563	Add to Cart
BHB20427516	T38752	25 mg	$1120	Add to Cart
BHB20427516	T38752	50 mg	$1830	Add to Cart
BHB20427516	T38752	100 mg	$2890	Add to Cart