EOS (d18:1/32:1/18:2)

Mfr.No.	T37461
Description	EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an omega-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid . The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12(R)-lipoxygenase (12(R)-LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss. Following oxygenation, the oxidized linoleate is hydrolyzed, leaving the omega-hydroxy end of the very long-chain fatty acid to covalently bind the protein layer, forming the corneocyte lipid envelope and sealing the gap between the extracellular lipid lamellae and the cornified cell envelope of the corneocyte.
Molecular Formula	C68H127NO5
Signaling Pathways	Others
Smiles	CCCCCCCCCCCCCC=C(CH)(O)(CH)(CO)NC(=O)CCCCCCCCCCCCCCCCCCCCC=C/CCCCCCCCCOC(=O)CCCCCCCC=C/CC=C/CCCCC
Cas Number	1318771-31-1
Molecular Weight	1038.766
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20426604	T37461	1 mg	$1232		Add to Cart