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Dyrk1A-IN-5

SKU : BHB20431805

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Description
Review(s)

Mfr.No.	T61739
Description	Dyrk1A-IN-5 (compound 5j) is a highly potent and selective inhibitor of DYRK1A, exhibiting an IC50 of 6 nM. It dose-dependently diminishes the phosphorylation of Thr434 in SF3B1, with an IC50 of 0.5 uM. Moreover, Dyrk1A-IN-5 effectively inhibits the phosphorylation of tau at Thr212, with an IC50 of 2.1 uM. Given these properties, Dyrk1A-IN-5 is a valuable tool for Down syndrome research (1).
Molecular Formula	C16H9IN2O2
Signaling Pathways	Others
Smiles	C(O)(=O)C1=C2C(=C3C(=N1)C=CC=C3)NC=4C2=CC=CC4I
Cas Number	1685235-41-9
Molecular Weight	388.16
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20431805	T61739	25 mg	$1070	Add to Cart
BHB20431805	T61739	50 mg	$1390	Add to Cart
BHB20431805	T61739	100 mg	$2190	Add to Cart

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Dyrk1A-IN-5

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