CBR-2092

Mfr.No.	T26963
Description	CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor. CBR-2092 exhibited rifampin-like potency as an inhibitor of RNA polymerase, was an equipotent (balanced) inhibitor of DNA gyrase and DNA topoisomerase IV, and retained activity against a prevalent quinolone-resistant variant. Studies of mutant strains that exhibited reduced susceptibility to CBR-2092 further substantiated RNA polymerase as the primary cellular target of CBR-2092, with DNA gyrase and DNA topoisomerase IV being secondary and tertiary targets, respectively, in strains exhibiting preexisting rifampin resistance.
Alternative Names	CBR 2092
Molecular Formula	C65H81FN6O15
Signaling Pathways	Others
Smiles	CO(CH)1C=C/O(C)2(C)Oc3c(C2=O)c2c(O)c(C=NN4CCC(CC4)N(C)C4(CC4)(CH)4CCN(C4)c4c(F)cn5c(c4C)c(cc(C(O)=O)c5=O)C4CC4)c(NC(=O)C(C)=C/C=C(CH)(C)(CH)(O)(CH)(C)(CH)(O)(CH)(C)(CH)(OC(C)=O)(CH)1C)c(O)c2c(O)c3C \|c:3,66,68\|
Cas Number	922717-97-3
Molecular Weight	1205.388
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20416848	T26963	25 mg	$1520		Add to Cart