BP-1-102

Mfr.No.	T3708
Description	BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 nM), then blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 uM), and selectively inhibits migration, survival, growth, and invasion of Stat3-dependent tumor cells. The BP-1-102-mediated inhibition of aberrantly active Stat3 in tumor cells suppresses the expression of c-Myc, Bcl-xL, Cyclin D1, Survivin, and VEGF.
Molecular Formula	C29H27F5N2O6S
Signaling Pathways	JAK/STAT signaling, Stem Cells
Smiles	N(CC1=CC=C(C=C1)C2CCCCC2)(C(CN(S(=O)(=O)C3=C(F)C(F)=C(F)C(F)=C3F)C)=O)C4=CC(O)=C(C(O)=O)C=C4
Cas Number	1334493-07-0
Molecular Weight	626.59
Target	STAT

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SKU	Supplier No.	Size	Your price
BHB20426274	T3708	1 mL	$106	Add to Cart
BHB20426274	T3708	1 mg	$33	Add to Cart
BHB20426274	T3708	2 mg	$47	Add to Cart
BHB20426274	T3708	5 mg	$76	Add to Cart
BHB20426274	T3708	10 mg	$122	Add to Cart
BHB20426274	T3708	25 mg	$222	Add to Cart
BHB20426274	T3708	50 mg	$372	Add to Cart
BHB20426274	T3708	100 mg	$549	Add to Cart