Bml 277

Mfr.No.	SIH-436
Alternative Names	Chk2 Inhibitor II, Chk2 Inhibitor II hydrate, 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide hydrate
Appearance	Off-white solid
Function	CHK2 kinase inhibitor
Inchi	InChI=1S/C20H14ClN3O2/c21-14-4-8-16(9-5-14)26-15-6-1-12(2-7-15)20-23-17-10-3-13(19(22)25)11-18(17)24-20/h1-11H,(H2,22,25)(H,23,24)
Inchikey	UXGJAOIJSROTTN-UHFFFAOYSA-N
Mode Of Action	Inhibitor
Molecular Formula	C20H14ClN3O2
Pubchem Cid	9969021
Research Area	Cell Signaling ; Cancer ; Apoptosis ; Cancer Growth Inhibitors ; Tyrosine Kinase Inhibitors
Safety Phrases	Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Smiles	C1=CC(=CC=C1C2=NC3=C(N2)C=CC(=C3)C(=O)N)OC4=CC=C(C=C4)Cl
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	516480-79-8
Molecular Weight	363.8
Scientific Background	Bml 277 is a highly selective inhibitor of Chk2, making it a useful tool for dissecting the role of Chk2 in cellular signaling.
Solubility	Soluble in DMSO (20 mg/ml) or ethanol (20 mg/ml)
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Pereg Y., et al. (2006) Mol. Cell Biol. 26(18): 6819–6831.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900220-1	SIH-436-10MG	10 mg	$111		Add to Cart
BHB11900220-2	SIH-436-50MG	50 mg	$443		Add to Cart