azido-FTY720

Mfr.No.	T37548
Description	FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 is phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). Down-regulation of S1P1 receptors on T and B lymphocytes by FTY720 results in defective egress of these cells from spleen, lymph nodes, and Peyer's patch. azido-FTY720 is a highly photoreactive analog of FTY720 that can be used to identify receptor binding sites for this ligand.
Molecular Formula	C19H32N4O2
Signaling Pathways	Others
Smiles	CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1N=(N+)=(N-)
Cas Number	881914-35-8
Molecular Weight	348.491
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20426671	T37548	1 mg	$635	Add to Cart
BHB20426671	T37548	5 mg	$2760	Add to Cart
BHB20426671	T37548	100 ?g	$83	Add to Cart
BHB20426671	T37548	500 ?g	$358	Add to Cart