Arecaidine propargyl ester (hydrobromide)

Mfr.No.	T36241
Description	Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 uM, respectively). Arecaidine propargyl ester induces contractions in isolated guinea pig atrium (pD2= 8.67). It induces apoptosis and the production of reactive oxygen species (ROS) in U87 and U251 glioblastoma cells when used at a concentration of 100 uM.2Arecaidine propargyl ester decreases mean arterial blood pressure in normotensive cats (ED25= 1.9 nmol/kg).3It is toxic to house flies (Musca) when administered at a dose of 75 ug/fly.4
Molecular Formula	C10H14BrNO2
Signaling Pathways	Others
Smiles	Br.O=C(OCCC)C1=CCCN(C)C1
Cas Number	116511-28-5
Molecular Weight	260.13
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20425602	T36241	5 mg	$155	Add to Cart
BHB20425602	T36241	10 mg	$293	Add to Cart
BHB20425602	T36241	25 mg	$538	Add to Cart