Alofanib

Mfr.No.	T5122
Description	Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM). It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.
Alternative Names	RPT835
Molecular Formula	C19H15N3O6S
Signaling Pathways	Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
Smiles	N(S(=O)(=O)C1=CC(C(O)=O)=CC=C1)C2=C(N(=O)=O)C=C(C)C(=C2)C=3C=CC=NC3
Cas Number	1612888-66-0
Molecular Weight	413.4
Target	Apoptosis, FGFR

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SKU	Supplier No.	Size	Your price
BHB20429659	T5122	1 mL	$79	Add to Cart
BHB20429659	T5122	1 mg	$31	Add to Cart
BHB20429659	T5122	5 mg	$72	Add to Cart
BHB20429659	T5122	10 mg	$97	Add to Cart
BHB20429659	T5122	25 mg	$213	Add to Cart
BHB20429659	T5122	50 mg	$318	Add to Cart
BHB20429659	T5122	100 mg	$493	Add to Cart