11-trans Leukotriene C4

Mfr.No.	T37492
Description	11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative to LTC4 in ionophore-stimulated HMC-1 cells (a human mast cell line) and equine eosinophils, but not in human neutrophils or RBL-1 cells. It is nearly equipotent with LTC4 for contraction of guinea pig parenchymal and ileum. In a radioligand binding assay using guinea pig ileum as a cysteinyl leukotriene receptor preparation, the pKis for LTC4 and 11-trans LTC4 were determined to be 6.42 and 6.58, respectively.
Molecular Formula	C30H47N3O9S
Signaling Pathways	Others
Smiles	CCCCCC=C/CC=CC=CC=C(CH)(SC(CH)(NC(=O)CC(CH)(N)C(O)=O)C(=O)NCC(O)=O)(CH)(O)CCCC(O)=O
Cas Number	74841-69-3
Molecular Weight	625.78
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20426628	T37492	25 ?g	$413	Add to Cart
BHB20426628	T37492	50 ?g	$783	Add to Cart
BHB20426628	T37492	100 ?g	$1480	Add to Cart