11-cis Retinal

Mfr.No.	T38219
Description	11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to form all-trans retinal beginning the phototransduction cycle, which is the basis for mammalian vision. A G121L mutation in opsin allows 11-cis retinal to bind as a partial agonist and activate rhodopsin in the absence of light. In a moth model of carotenoid deficiency-induced low visual sensitivity, 11-cis retinal application to compound eyes restored visual sensitivity almost completely.
Molecular Formula	C20H28O
Signaling Pathways	Others
Smiles	C/C(/C=CC=C(/C)C=CC1=C(C)CCCC1(C)C)=CC=O \|c:9\|
Cas Number	564-87-4
Molecular Weight	284.443
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20427200	T38219	2 mg	$6720		Add to Cart