10(S),17(S)-DiHDHA

Mfr.No.	T37488
Description	Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA is a DHA metabolite, also referred to as protectin DX (PDX). It is produced by an apparent double lipoxygenase (LO)-mediated reaction in murine peritonitis exudates, in suspensions of human leukocytes, or by soybean 15-LO incubated with DHA. It differs from protectin D1 with respect to the stereochemistry of the C-10 hydroxyl and the double bond configuration at the 13 and 15 positions. 10(S),17(S)-DiHDHA blocks neutrophil infiltration in murine peritonitis by 20-25% at a dose of 1 ng/mouse. It also inhibits platelet activation by both impairing thromboxane (TX) synthesis and TX receptor activation.
Molecular Formula	C22H32O4
Signaling Pathways	Others
Smiles	CCC=C/C(CH)(O)C=CC=C/C=C/(CH)(O)CC=C/CC=C/CCC(O)=O
Cas Number	871826-47-0
Molecular Weight	360.494
Target	Others

Have you used this product?

SKU	Supplier No.	Size	Your price
BHB20426625	T37488	25 ?g	$455	Add to Cart
BHB20426625	T37488	50 ?g	$793	Add to Cart
BHB20426625	T37488	100 ?g	$1530	Add to Cart