1-?-D-Glucosylsphingadienine (d18:2 (4E,8E))

Mfr.No.	T38213
Description	1-beta-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 uM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher's disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3); thus, glucosylsphingosine has been used as a key biomarker of the disease. This product contains 1-beta-D-glucosylsphingadienine isolated from plants.
Molecular Formula	C24H45NO7
Signaling Pathways	Others
Smiles	CCCCCCCCCC=CCCC=CC(O)C(N)COC1OC(CO)C(O)C(O)C1O \|w:14.14,10.10\|
Cas Number	114200-59-8
Molecular Weight	459.624
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20427194	T38213	1 mg	$293		Add to Cart