Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
Source
Mammalian cell
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
Weight
22.25kDa
Stotage Note
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer
Tris-based buffer,50% glycerol
Purity
Greater than 90% as determined by SDS-PAGE.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer
Tris-based buffer,50% glycerol
Immunogen Species
Rhesus
Reviews of Recombinant Macaca mulatta Erythropoietin (EPO)