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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human Tumor necrosis factor receptor superfamily member 5 (CD40), partial (Active)

BHP10506917
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Email
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Involvement In Disease Immunodeficiency with hyper-IgM 3 (HIGM3)
Subcellular Location Isoform I: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform II: Secreted
Uniprot P25942
Database Links

HGNC:11919

OMIM:109535

KEGG:hsa:958

STRING:9606.ENSP00000361359

UniGene:Hs.472860
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Pathway NF-kappa B signaling pathway; Toll-like receptor signaling pathway
Research Area Immunology
Tissue Specificity B-cells and in primary carcinomas.
Antigen CD40
Purity Greater than 95% as determined by SDS-PAGE.
Storage Buffer Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.4
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10506917 CSB-AP005181HU 10ug $184
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BHP10506917 CSB-AP005181HU 50ug $484
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BHP10506917 CSB-AP005181HU 500ug $2978
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BHP10506917 CSB-AP005181HU 1mg $4254
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