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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human Nectin-4 (NECTIN4), partial (Active)

BHP10506546
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Involvement In Disease Ectodermal dysplasia-syndactyly syndrome 1 (EDSS1)
Subcellular Location Cell membrane, Single-pass type I membrane protein, Cell junction, adherens junction, Note=Colocalizes with AFDN at cadherin-based adherens junctions (PubMed:11544254), SUBCELLULAR LOCATION: Processed poliovirus receptor-related protein 4: Secreted
Uniprot Q96NY8
Database Links

HGNC:19688

OMIM:609607

KEGG:hsa:81607

STRING:9606.ENSP00000356991

UniGene:Hs.492490
Function Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.; FUNCTION
Pathway Adherens junction
Protein Families Nectin family
Research Area Cell Biology
Tissue Specificity Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma.
Antigen NECTIN4
Purity Greater than 95% as determined by SDS-PAGE.
Storage Buffer Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.4
Immunogen Species Homo Sapiens (Human)
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BHP10506546 CSB-AP005571HU 10ug $174
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BHP10506546 CSB-AP005571HU 50ug $484
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BHP10506546 CSB-AP005571HU 500ug $2030
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BHP10506546 CSB-AP005571HU 1mg $3094
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