Recombinant Human Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1), partial

Mfr.No.	CSB-EP010600HU
Alternative Names	Helix-destabilizing protein,Single-strand RNA-binding proteinhnRNP core protein A1, Helix-destabilizing protein ; Single-strand RNA-binding proteinhnRNP core protein A1
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	2-354aa
Mol Weight	40.9kDa
Nature	recombinant
Protein Description	Partial

Involvement In Disease	Inclusion body myopathy with early-onset Paget disease with or without frontotemporal dementia 3 (IBMPFD3); Amyotrophic lateral sclerosis 20 (ALS20)
Subcellular Location	Nucleus, Cytoplasm, Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs, Shuttles continuously between the nucleus and the cytoplasm along with mRNA, Component of ribonucleosomes (PubMed:17289661), SUBCELLULAR LOCATION: Cytoplasm
Uniprot	P09651, P09651
Database Links	HGNC:5031 OMIM:164017 KEGG:hsa:3178 STRING:9606.ENSP00000341826 UniGene:Hs.546261
Function	Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection
Research Area	Immunology
Weight	41kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol