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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human Draxin (DRAXIN)

SKU : BHP10503175

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP822750HU
Alternative Names	Dorsal inhibitory axon guidance protein, Dorsal repulsive axon guidance protein, Neucrin, Dorsal inhibitory axon guidance protein ; Dorsal repulsive axon guidance protein ; Neucrin
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	26-349aa
Mol Weight	52.0kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	Q8NBI3, Q8NBI3
Database Links	HGNC:25054 OMIM:612682 KEGG:hsa:374946 STRING:9606.ENSP00000294485 UniGene:Hs.632364
Function	Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
Protein Families	Draxin family
Research Area	Neuroscience
Weight	52.01kDa
Antigen	DRAXIN

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503175	CSB-EP822750HU	20ug	$306		Add to Cart
BHP10503175	CSB-EP822750HU	100ug	$578		Add to Cart
BHP10503175	CSB-EP822750HU	1mg	$2466		Add to Cart

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