Recombinant Human Delta-like protein 3 (DLL3), partial

Mfr.No.	CSB-YP882142HU
Alternative Names	Drosophila Delta homolog 3 ,Delta3, Drosophila Delta homolog 3 ; Delta3
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm .
Source	Yeast
Abbreviation	DLL3
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Delta-like protein 3; Alternative name(s): Drosophila Delta homolog 3; Short name= Delta3
Expression Region	27-492aa
Mol Weight	50.5kDa
Nature	recombinant
Protein Description	Partial

Involvement In Disease	Spondylocostal dysostosis 1, autosomal recessive (SCDO1)
Subcellular Location	Membrane, Single-pass type I membrane protein
Uniprot	Q9NYJ7, Q9NYJ7
Database Links	HGNC:2909 OMIM:277300 KEGG:hsa:10683 STRING:9606.ENSP00000205143 UniGene:Hs.127792
Function	Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
Pathway	Notch signaling pathway; Th1 and Th2 cell differentiation
Research Area	Developmental Biology
Weight	50.5kDa
Antigen	DLL3

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol