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Home / Proteins & Peptide / Recombinant Protein

Recombinant Horse Interleukin-1 Receptor Antagonist protein (IL1RN) (Active)

SKU : BHP10506002

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-AP003491HO
Description	Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Alternative Names	Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, Alternative name(s):, IL1 inhibitor, Interleukin-1 receptor antagonist protein Short name: IL-1RN Short name: IL-1ra Short name: IRAP Alternative name(s): IL1 inhibitor
Pubmed Id	19157767
Tag	Tag-Free
Regulatory	RUO
Source	E.coli
Endotoxin Level	Less than 1.0 EU/μg as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α- dependent proliferation of murine D10S cells is less than 3.0 μg/ml, corresponding to a specific activity of >333 IU/mg in the presence of 50 pg/ml rHuIL-1α.
Biological Activity Comment	Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α- dependent proliferation of murine D10S cells is less than 3.0 μg/ml, corresponding to a specific activity of ＞ 333 IU/mg in the presence of 50 pg/ml rHuIL-1α.
Expression Region	26-177aa
Mol Weight	17.4 kDa
Nature	Recombinant
Protein Description	Full Length of Mature Protein
Protein Length	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	O18999, O18999
Database Links	KEGG:ecb:100034236 STRING:9796.ENSECAP00000004056 UniGene:Eca.13123
Function	Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Protein Families	IL-1 family
Research Area	Immunology
Weight	17.4 kDa
Antigen	IL1RN

Buffer	0.2 µm filtered PBS, pH 7.4 ,lyophilized
Purity	>95% as determined by SDS-PAGE and HPLC.
Storage Buffer	0.2 μm filtered PBS, pH 7.4 ,lyophilized

Immunogen Species	Equus Caballus (Horse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10506002	CSB-AP003491HO	5ug	$142		Add to Cart
BHP10506002	CSB-AP003491HO	100ug	$852		Add to Cart
BHP10506002	CSB-AP003491HO	500ug	$1910		Add to Cart

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