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Home / Primary Antibodies / Recombinant Antibodies

Tau Antibody (pSer202/ pThr205), Clone AH36 (SMC-601)

SKU : BHA11933283

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StressMarq Biosciences Inc.

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Mfr.No.	SMC-601, SMC-601D, SMC-601D-A390, SMC-601D-A488, SMC-601D-A594, SMC-601D-APC, SMC-601D-BI, SMC-601D-FITC, SMC-601D-HRP, SMC-601D-PCP, SMC-601D-RPE, SMC-601S
Immunogen Species	Human
Alternative Names	Tau Antibody, Neurofibrillary tangle protein Antibody, MAPTL Antibody, Microtubule-associated protein tau Antibody, MTBT1 Antibody, Paired helical filament-tau Antibody, TAU Antibody, PHF-tau Antibody, MAPT Antibody, AI413597 antibody, AW045860 antibody, DDPAC antibody, FLJ31424 antibody, FTDP 17 antibody, G protein beta1/gamma2 subunit interacting factor 1 antibody, MAPT antibody, MAPTL antibody, MGC134287 antibody, MGC138549 antibody, MGC156663 antibody, Microtubule associated protein tau antibody, Microtubule associated protein tau isoform 4 antibody, Microtubule-associated protein tau antibody, MSTD antibody, Mtapt antibody, MTBT1 antibody, MTBT2 antibody, Neurofibrillary tangle protein antibody, Paired helical filament tau antibody, Paired helical filament-tau antibody, PHF tau antibody, PHF-tau antibody, PPND antibody, PPP1R103 antibody, Protein phosphatase 1, regulatory subunit 103 antibody, pTau antibody, RNPTAU antibody, TAU antibody, TAU_HUMAN antibody, Tauopathy and respiratory failure, included antibody, AT8 antibody, phospho tau antibody
Categories	Antibodies
Cellular Localization	Cytoskeleton, Cytosol, Plasma Membrane, Axon, Dendrite
Certificate Of Analysis	A 1:500 dilution of SMC-601 was sufficient for detection of Tau in 10 ug Baculovirus by dot blot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Rabbit Anti-Human Tau Monoclonal IgG
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen Region	Synthetic peptide of Human Phospho Tau (Ser202/Thr205)
Isotype	IgG
Launch Date	2019/07/05
Net Weight (g)	0.1
Reactivity	Human, Mouse
Species Reactivity Medium	Mouse, Human
Tissue Specificity	Expressed in neurons.

Antigen	Tau
Swissprot	P10636
Gene Id	4137
Clone No	AH36
Research Area	Tangles & Tau, Alzheimer's Disease, Axon Markers, Cell Markers, Cell Signaling, Microtubules, MT Associated Proteins, Neurodegeneration, Neuron Markers, Neuroscience, Cytoskeleton

Buffer	PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration	1 mg/ml
Purification	Affinity Purified
Scientific Background	Alzheimer s Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). Phosphorylation at serine 202 and threonine 205 induces a turn-like structure and drives tau aggregation (4). SMC-601 recognizes the same epitope as the AT8 phospho tau antibody.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~79 kDa.
Storage	-20ÂºC
Storage Buffer	PBS pH 7.4, 50% glycerol, 0.09% Sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	WB, DB, ICC/IF, ELISA, IHC
Dilution	WB (1:500), ICC/IF (1:500); IHC (1:500); optimal dilutions for assays should be determined by the user.

Product Manual	SDS

Reference	1. www.alz.org/alzheimers-dementia/facts-figures 2. Alzheimer, A. Über eine eigenartige Erkrankung der Hirnrinde. Allg. Z. Psychiatr. Psych.-Gerichtl. Med. 64, 146148 (1907) 3. Matsumoto, G. et al. (2018). Int J Mol Sci. 19, 1497. 4. Depres, C. et al. (2017). PNAS 114(34):9080-9085.

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Combination SKU	Supplier No.	Conjugate	Size	Your price	Quantity
BHA11933283-1	SMC-601D	Unconjugated	100 ug	$487		Add to Cart
BHA11933283-2	SMC-601D-A390	ATTO 390	100 ug	$541		Add to Cart
BHA11933283-3	SMC-601D-A488	ATTO 488	100 ug	$540		Add to Cart
BHA11933283-4	SMC-601D-A594	ATTO 594	100 ug	$540		Add to Cart
BHA11933283-5	SMC-601D-APC	APC	100 ug	$539		Add to Cart
BHA11933283-6	SMC-601D-BI	Biotin	100 ug	$536		Add to Cart
BHA11933283-7	SMC-601D-FITC	FITC	100 ug	$530		Add to Cart
BHA11933283-8	SMC-601D-HRP	HRP	100 ug	$526		Add to Cart
BHA11933283-9	SMC-601D-PCP	PerCP	100 ug	$539		Add to Cart
BHA11933283-10	SMC-601D-RPE	RPE	100 ug	$537		Add to Cart
BHA11933283-11	SMC-601S	Unconjugated	12 ug	$45		Add to Cart

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