Anti-undefined Antibody TYRP1,2340R Unconjugated BHA10208310

Mfr.No.	7306-RBM8-P1ABX
Alternative Names	5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	9p23
Clonality	monoclonal
Description	It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Host	Rabbit
Immunogen	Recombinant fragment of human TYRP1 protein (around aa 257-377) (exact sequence is proprietary)
Isotype	IgG
Positive Control	SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Human Skin or Melanoma.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P17643
Gene Id	7306
Clone No	TYRP1, 2340R
Symbol	TYRP1
Weight	75kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

ELISA, IHC-F

Description

Order Ab without BSA, Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., ELISA ; IHC-F

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
Immunohistology (Formalin-fixed)	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208310	7306-RBM8-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody TYRP1,2340R Unconjugated BHA10208310

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