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Home / Primary Antibodies / Recombinant Antibodies

Anti-EIF2AK2 Antibody BHA11308929

SKU : BHA11308929

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Mfr.No.	BS9905M
Alternative Names	Interferon-induced ; double-stranded RNA-activated protein kinase ; Eukaryotic translation initiation factor 2-alpha kinase 2 ; eIF-2A protein kinase 2 ; Interferon-inducible RNA-dependent protein kinase ; P1/eIF-2A protein kinase ; Protein kinase RNA-activated ; PKR ; Tyrosine-protein kinase EIF2AK2 ; p68 kinase ; PKR ; PRKR ; EIF2AK2
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	2p22.2
Clonality	monoclonal
Description	An interferon-inducible, RNA-dependent protein serine/threonine kinase (PKR) has been described. PKR in earlier literature is variously known as DAI, dsJ, PI kinase, p65, p67 or TIK for the mouse kinase; and p68 or p69 for the human kinase. The PKR kinase substrate is the α subunit of protein synthesis initiation factor eIF-2. Phosphorylation of eIF-2α on serine-51 results in inhibition of translation. Molecular cDNA clones have been isolated from both human and mouse cells. The serine/threonine kinase catalytic domains map to the carboxy terminal half of the protein while the RNA-binding domains are located in the amino terminal region. Three kinds of regulation of PKR enzymatic activity have been described.
Host	Rabbit
Immunogen	Recombinant antibody.
Modification	phospho-T446
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P19525
Uniprot	P19525
Weight	62 kDa

Description	Product: Recombinant Rabbit Monoclonal Antibody. 1TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. Specificity:* This antibody detects endogenous levels of human PKR protein only when phosphorylated at Thr446.
Purity	Protein A affinity purified
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:1,000-1:2,000
IHC	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308929	BS9905M	50µl	$279.33		Add to Cart
BHA11308929	BS9905M	100µl	$403.78		Add to Cart

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