WDR45

Mfr.No.	SPC-651, SPC-651D, SPC-651D-A390, SPC-651D-A488, SPC-651D-A594, SPC-651D-APC, SPC-651D-BI, SPC-651D-FITC, SPC-651D-HRP, SPC-651D-PCP, SPC-651D-RPE, SPC-651S
Immunogen Species	Human
Alternative Names	WIPI4 Antibody, WDR45 Antibody, WDRX1 Antibody, WD repeat domain phosphoinositide-interacting protein 4 Antibody, WIPI-4 Antibody, WDRXI4 Antibody, WD repeat-containing protein 45 Antibody, ORF Names: Antibody, JM5 Antibody
Categories	Antibodies
Certificate Of Analysis	A 1:1000 dilution of SPC-651 was sufficient for detection of WIPI4 in 15 ug of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human WDR45 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322), Homo Sapiens (Human)
Immunogen Region	Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Rat, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Rat, Human
Tissue Specificity	Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.

Antigen	WDR45
Swissprot	Q9Y484
Accession Number	NP_001025067.1
Gene Id	11152
Target	WDR45
Research Area	Cancer, Autophagy, Cell Signaling, Apoptosis

Buffer	PBS, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.
Scientific Background	WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~40 kDa.
Storage	-20ºC
Storage Buffer	PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	WB, ICC/IF
Description	WB ; ICC ; IF
Dilution	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

Reference	1. http://www.genecards.org/cgi-bin/carddisp.pl gene=WDR45 2. Strausberg R.L., et al. (2002) Proc Natl Acad Sci U S A. 99(26): 1689916903. 3. Haack T.B., et al. (2012) Am J Hum Genet. 91(6): 11441149.

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11908698-1	SPC-651D	Unconjugated	100 ug	$338	Add to Cart
BHA11908698-2	SPC-651D-A390	ATTO 390	100 ug	$393	Add to Cart
BHA11908698-3	SPC-651D-A488	ATTO 488	100 ug	$392	Add to Cart
BHA11908698-4	SPC-651D-A594	ATTO 594	100 ug	$392	Add to Cart
BHA11908698-5	SPC-651D-APC	APC	100 ug	$391	Add to Cart
BHA11908698-6	SPC-651D-BI	Biotin	100 ug	$388	Add to Cart
BHA11908698-7	SPC-651D-FITC	FITC	100 ug	$383	Add to Cart
BHA11908698-8	SPC-651D-HRP	HRP	100 ug	$378	Add to Cart
BHA11908698-9	SPC-651D-PCP	PerCP	100 ug	$391	Add to Cart
BHA11908698-10	SPC-651D-RPE	RPE	100 ug	$389	Add to Cart
BHA11908698-11	SPC-651S	Unconjugated	12 ug	$45	Add to Cart

Rabbit Anti-Human WDR45 Polyclonal (SPC-651)