NDR1 (pSer281+pThr282)

Mfr.No.	SPC-1035, SPC-1035D, SPC-1035D-A390, SPC-1035D-A488, SPC-1035D-A594, SPC-1035D-BI, SPC-1035D-FITC
Immunogen Species	Human
Alternative Names	NDR 1 antibody, NDR antibody, Ndr Ser/Thr kinase-like protein antibody, NDR1 antibody, NDR1 protein kinase antibody, Nuclear Dbf2 related kinase 1 antibody, Serine/threonine protein kinase 38 antibody, STK 38 antibody, STK38 antibody, STK38_HUMAN antibody
Categories	Antibodies
Cellular Localization	Nucleus, Cytoplasm
Certificate Of Analysis	A 1:250 dilution of SPC-1035 was sufficient for detection of NDR1 (pSer281+pThr282) in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human NDR1 (pSer281+pThr282) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Ser281 and Thr282 of human NDR1 (AA278-285), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Ser281 and Thr282 of human NDR1 (AA278-285)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Ubiquitously expressed with highest levels observed in peripheral blood leukocytes.

Antigen	NDR1
Swissprot	Q15208
Accession Number	NP_009202
Gene Id	11329
Target	NDR1 (pSer281+pThr282)
Research Area	Neurodegeneration, Cancer, Tumor Biomarkers, Oncoproteins, Signal Transducers, Cardiovascular System, Angiogenesis, Neuroscience

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Ubiquitously expressed with highest levels observed in peripheral blood leukocytes.
Scientific Background	STK38 is a negative regulator of MAP3K1/2 signalling. Converts MAP3K2 from its phosphorylated form to its nonphosphorylated form and inhibits autophosphorylation of MAP3K2. The MAPK/ERK pathway has been implicated in oncogenesis as either a promoter or inhibitor depending on the cancer system. Thus, the role of STK38 in cancer is likely highly contextual.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 54.19 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11913446-1	SPC-1035D	Unconjugated	100 ul	$338	Add to Cart
BHA11913446-2	SPC-1035D-A390	ATTO 390	100 ul	$393	Add to Cart
BHA11913446-3	SPC-1035D-A488	ATTO 488	100 ul	$392	Add to Cart
BHA11913446-4	SPC-1035D-A594	ATTO 594	100 ul	$392	Add to Cart
BHA11913446-5	SPC-1035D-BI	Biotin	100 ul	$388	Add to Cart
BHA11913446-6	SPC-1035D-FITC	FITC	100 ul	$383	Add to Cart

Rabbit Anti-Human NDR1 (pSer281+pThr282) Polyclonal (SPC-1035)