BRSK1 (pThr189)

Mfr.No.	SPC-927, SPC-927D, SPC-927D-A390, SPC-927D-A488, SPC-927D-A594, SPC-927D-BI, SPC-927D-FITC
Immunogen Species	Human
Alternative Names	Brain selective kinase 1 Antibody, Brain-specific serine/threonine-protein kinase 1 Antibody, BRSK 1 Antibody, hSAD1 Antibody, SAD1 Antibody, SADB Antibody, Serine/threonine kinase SAD B Antibody
Categories	Antibodies
Cellular Localization	Cytoplasm, Nucleus
Certificate Of Analysis	A 1:250 dilution of SPC-927 was sufficient for detection of BRSK1 (pThr189) in 10 ug of human brain lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human BRSK1 (pThr189) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Thr189 of human BRSK1 (AA186-192), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Thr189 of human BRSK1 (AA186-192)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human

Antigen	BRSK1
Swissprot	Q8TDC3
Accession Number	NP_115806
Gene Id	84446
Target	BRSK1 (pThr189)
Research Area	Cancer, Cell Cycle, Cell Signaling, Protein Phosphorylation

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Scientific Background	BRSK1 (BR serine/threonine-protein kinase 1), also known as SAD1, is a 794 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one UBA domain and one protein kinase domain. Expressed in a variety of tissues with highest expression in testis and brain, BRSK1 uses magensium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins, including Wee 1 and Cdc25B. Via its kinase activity toward proteins that are involved in microtubule assembly, BRSK1 plays an essential role in neuronal polarization and may be involved in regulating cell cycle arrest in response to DNA damage, Two isoforms of BRSK1 exist due to alternative splicing events.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 86.753 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11911502-1	SPC-927D	Unconjugated	100 ul	$338	Add to Cart
BHA11911502-2	SPC-927D-A390	ATTO 390	100 ul	$393	Add to Cart
BHA11911502-3	SPC-927D-A488	ATTO 488	100 ul	$392	Add to Cart
BHA11911502-4	SPC-927D-A594	ATTO 594	100 ul	$392	Add to Cart
BHA11911502-5	SPC-927D-BI	Biotin	100 ul	$388	Add to Cart
BHA11911502-6	SPC-927D-FITC	FITC	100 ul	$383	Add to Cart

Rabbit Anti-Human BRSK1 (pThr189) Polyclonal (SPC-927)