Mouse TIM-3, also known as T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, and KIM-3. GenBank Accession No. NM_032782, a.a. 22-191, expressed in a HEK293 cells expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag technology. MW = 47 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Immunogen Region
22-191
Tag
C-terminal Fc-Avi-Tag, Biotin-Labeled
Formulation
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Mouse
Notes
HiP indicates a high purity protein with>=90% purity as measured by gel filtration. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_032782
Mw(kda)
47 kDa
Synonyms
T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, KIM-3
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution.
Storage
At least 6 months at -80°C.
Reference
1. Zhu, C. et al., Nat. Immunol. 2005; 6:1245-12525.2. Anderson, A.C. et al., Science. 2007; 318(5853):1141-1143.