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Home / Proteins & Peptide

Recombinant SARS-CoV-2 Spike RBD(N501Y)(His Tag)

SKU : BHP10306318

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSV030318
Reconstitution	Please refer to the printed manual for detailed information.
Background	Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Tag	C-His
Formulation	Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
Species	SARS-CoV-2
Host	Mammalian cells
Accession Number	YP_009724390.1
Endotoxin Level	Please contact us for more information.
Predicted Molecular Mass(kd)	35kDa
Protein Description	Recombinant SARS-CoV-2 S Protein RBD(N501Y) is produced by Mammalian cells expression system and the target gene is expressed with C-His Tag

Synonyms	RBD Protein, Spike RBD Protei,UK variant (B.1.1.7)
Research Area	Virus related Protein

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Purity	>90% as determined by SDS-PAGE
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at< -20°C for 3 months.

Immunological Activity	Test in progress

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SKU	Supplier No.	Size	Your price	Quantity
BHP10306318	PKSV030318	100ug	$645		Add to Cart
BHP10306318	PKSV030318	1mg	-		Add to Cart

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