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Home / Proteins & Peptide

Recombinant Saccharomyces cerevisiae Nicotinamidase(PNC1)

SKU : BHP10504587

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP346834SVG
Description	Catalyzes the deamidation of nicotinamide, an early step in the NAD+ salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate.
Alternative Names	Nicotine deamidase, NAMase, Nicotine deamidase Short name: NAMase
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Catalyzes the deamidation of nicotinamide, an early step in the NAD+ salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Nicotinamidase; EC= 3.5.1.19; Alternative name(s): Nicotine deamidase; Short name= NAMase
Expression Region	1-216aa
Mol Weight	29.0kDa
Nature	Recombinant
Protein Description	Full Length

Subcellular Location	Cytoplasm, Nucleus, Peroxisome
Uniprot	P53184, P53184
Database Links	KEGG:sce:YGL037C STRING:4932.YGL037C
Function	Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate.
Protein Families	Isochorismatase family
Research Area	Microbiology
Weight	29 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Saccharomyces Cerivisiae (Yeast)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10504587	CSB-EP346834SVG	1mg	$2466		Add to Cart
BHP10504587	CSB-EP346834SVG	100ug	$729		Add to Cart
BHP10504587	CSB-EP346834SVG	20ug	$388		Add to Cart

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