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Home / Proteins & Peptide

Recombinant Rat HER2/ErbB2 Protein (aa 67-323, His Tag)

SKU : BHP10305846

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030455
Alternative Names	Receptor tyrosine-protein kinase erbB-2; Epidermal growth factor receptor-related protein; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; p185erbB2; p185neu; CD340; ERBB2;ENV;ENVW;ERVWE1;HER-2;HER-2/neu;HER2;HERV-7q;HERV-W-ENV;HERV7Q;HERVW;HERVWENV;MLN 19;MLN19
Reconstitution	Please refer to the printed manual for detailed information.
Background	ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB2 mediates signalling pathways which involve mitogen-activated protein kinase and phosphatidylinositol-3 kinase, this receptor plays a key role in development, cell proliferation and differentiation.
Reactivity	Rat
Tag	C-6His
Description	Recombinant Rat Receptor tyrosine-protein kinase ErbB-2 is produced by our E.coli expression system and the target gene encoding Ala67-Val323 is expressed with a 6His tag at the C-terminus.
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NaCl, 4M Urea, pH 8.0.
Host	E.coli
Accession Number	P06494
Endotoxin Level	<1.0 EU per ?g as determined by LAL test.
Mol Weight	29.3 kDa
Mw(kda)	29.3 kDa

Sequence Info	Ala67-Val323

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305846	PKSR030455	10ug	$117		Add to Cart
BHP10305846	PKSR030455	50ug	$297		Add to Cart

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