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Home / Proteins & Peptide

Recombinant Rat ESAM Protein (Fc Tag)

SKU : BHP10305748

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSR030296
Alternative Names	ESAM
Reconstitution	Please refer to the printed manual for detailed information.
Background	Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth.
Reactivity	Rat
Tag	C-Fc
Description	A DNA sequence encoding the rat ESAM (Q6AYD4) extracellular domain (Met 1-Ala 251) was fused with the Fc region of human IgG1 at the C-terminus.
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	Q6AYD4
Endotoxin Level	< 1.0 EU per ?g of the protein as determined by the LAL method
Mol Weight	51.2 kDa
Mw(kda)	51.2 kDa

Sequence Info	Met 1-Ala 251

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 85 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305748	PKSR030296	100ug	$732		Add to Cart

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