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Recombinant Mouse VEGF Receptor 2/VEGF R2/FLK-1/KDR (C-Fc)

SKU : BHP10305642

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM041405
Description	Recombinant Mouse Vascular Endothelial Growth Factor Receptor 2 is produced by our Mammalian expression system and the target gene encoding Ala20-Glu762 is expressed with a Fc tag at the C-terminus.
Alternative Names	VEGFR2; VEGF R2; Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; Fetal liver kinase 1; FLK-1;Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1
Reconstitution	Please refer to the printed manual for detailed information.
Background	Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. It also plays an essential role in promoting proliferation, survival, migration and differentiation of endothelial cells, reorganization of the actin cytoskeleton. VEGFR2 is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo.The adaptor protein SHB has been shown to interact with VEGFR2 in receptor tyrosine kinase signaling. In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
Reactivity	Mouse
Tag	C-Fc
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Host	Human Cells
Accession Number	P35918
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	110 kDa
Mw(kda)	110 kDa

Sequence Info	Ala20-Glu762

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	>95% as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305642	PKSM041405	10ug	$104		Add to Cart
BHP10305642	PKSM041405	50ug	$312		Add to Cart

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