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Home / Proteins & Peptide

Recombinant Mouse Transforming Growth Factor-Beta Receptor Type II/TGFBR2 (C-Fc)

SKU : BHP10305654

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM041417
Description	Recombinant Mouse Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Ile24-Asp184 is expressed with a Fc tag at the C-terminus.
Alternative Names	TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II; Tgfbr2
Reconstitution	Please refer to the printed manual for detailed information.
Background	Transforming growth factor-beta (TGF-beta) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-beta regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-beta receptor type I (TGF-beta-RI), TGF-beta receptor type II (TGF-beta-RII), and TGF-betabeta receptor type III (TGF-beta-RIII). TGF-beta RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-beta) receptor subfamily. TGF-beta RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.
Reactivity	Mouse
Tag	C-Fc
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Host	Human Cells
Accession Number	Q62312
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	45 kDa
Mw(kda)	45 kDa

Sequence Info	Ile24-Asp184

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	>95% as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305654	PKSM041417	10ug	$210		Add to Cart
BHP10305654	PKSM041417	50ug	$630		Add to Cart

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