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Home / Proteins & Peptide

Recombinant Mouse TGF?1/TGFB1 Protein (Active)

SKU : BHP10305411

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM041167
Alternative Names	TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP;latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1
Reconstitution	Please refer to the printed manual for detailed information.
Background	Transforming growth factor beta 1 (TGFbeta1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-beta1, TGF-beta2 and TGF-beta3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-beta receptor type II (TbetaR-II), and a TGF-beta receptor type I (TbetaR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-beta expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
Reactivity	Mouse
Description	Recombinant Mouse Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.
Formulation	Lyophilized from a 0.2 um filtered solution of 50mM Glycine,150mM NaCl,pH 2.5.
Host	Human Cells
Accession Number	P04202
Endotoxin Level	< 1.0 EU per ?g as determined by the LAL method.
Bioactivity	Measured by its ability to inhibit IL-4-dependent proliferation of TF?1 human erythroleukemic cells. The ED50 for this effect is 5-25 pg/ml.
Mol Weight	12.8 kDa
Mw(kda)	12.8 kDa

Sequence Info	Ala279-Ser390

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305411	PKSM041167	10ug	$178		Add to Cart
BHP10305411	PKSM041167	50ug	$523		Add to Cart

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