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Home / Proteins & Peptide

Recombinant Mouse SHH

SKU : BHP10900680

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z200615
Description	Mouse SHH is part of a small group of secreted proteins that are vital for development in both vertebrates and invertebrates. Mouse SHH shares 99% homology with the human gene for SHH. Sonic HedgeHog is a protein that is vital in guiding the early embryo; it has been associated as the major inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. SHH binds to the patched receptor to activate the transcription of target genes. Sonic HedgeHog also regulates another factor, the gli oncogene. Recombinant Mouse SHH is a single, non-glycosylated polypeptide chain of 19.8 kDa.
Alternative Names	Sonic hedgehog protein ; HHG-1,
Quantity	25 µg
Regulatory	RUO
Source	E. coli
Host	Mouse
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	The ED50 of this protein, as measured by its ability to induce alkaline phosphatase production in mouse myoblast cell, was in the range of 500ng-3 ug/mL.

Weight	19.8 kDa

Format	Lyophilized Powder Lyophilized from a 0.2 µm filtered solution in phosphate buffer and NaCl
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.

Immunogen Species	Mus Musculus (Mouse)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900680	Z200615	25µg	$109.44		Add to Cart

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