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Home / Proteins & Peptide / Recombinant Protein

Recombinant Mouse Cytotoxic T-lymphocyte protein 4 (Ctla4), partial (Active)

SKU : BHP10506748

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-AP005301MO
Alternative Names	Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, Ctla4
Source	Mammalian cell
Endotoxin Level	Less than 1.0 EU/μg as determined by LAL method.
Bioactivity	The ED50 as determined by its ability to bind Mouse B7-1 in functional ELISA is less than 20 ng/ml.
Expression Region	37-161aa
Mol Weight	14.6 kDa
Protein Description	Partial

Subcellular Location	Cell membrane, Single-pass type I membrane protein
Uniprot	P09793
Database Links	KEGG:mmu:12477 STRING:10090.ENSMUSP00000027164 UniGene:Mm.390
Function	Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Pathway	T cell receptor signaling pathway
Research Area	Immunology
Tissue Specificity	Widely expressed with highest levels in lymphoid tissues.
Antigen	CTLA4

Purity	Greater than 95% as determined by SDS-PAGE.
Storage Buffer	Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10506748	CSB-AP005301MO	10ug	$96		Add to Cart
BHP10506748	CSB-AP005301MO	50ug	$232		Add to Cart
BHP10506748	CSB-AP005301MO	500ug	$1422		Add to Cart
BHP10506748	CSB-AP005301MO	1mg	$2030		Add to Cart

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