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Home / Proteins & Peptide

Recombinant Mouse CD5 Protein (aa 24-370, His Tag)

SKU : BHP10305466

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSM041222
Alternative Names	T-cell surface glycoprotein CD5; CD5; CD5 antigen; CD5 antigen (p56-62); CD5 molecule; LEU1T-cell surface glycoprotein CD5; Lymphocyte antigen T1;Leu-1; T1; Ly-1
Reconstitution	Please refer to it for detailed information.
Background	CD5 is a transmembrane glycoprotein of the conserved scavenger receptor cysteine-rich (SRCR) superfamily and expressed on thymocytes, peripheral T cells and a subset of B cells (B1-a). Moreover, CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. The long cytoplasmic tail of CD5 has no intrinsic enzymatic activity, but contains four tyrosine phosphorylation sites, including an immunoreceptor tyrosine-based (ITAM)-like motif (pseudo-ITAM) and an immunoreceptor tyrosine-based inhibitory (ITIM)-like motif (pseudo-ITIM), as well as multiple potential serine and threonine phosphorylation sites. It physically associates with the T cell antigen receptor (TCR) and B cell antigen receptor (BCR), where it negatively modulates the activation and differentiation signals transduced by these receptors. CD5 also plays an important role in protection from activation-induced cell death and in the recognition of pathogen associated molecular patterns (PAMPS) present on fungal surfaces.
Reactivity	Mouse
Tag	C-6His
Description	Recombinant Mouse T-Cell Surface Glycoprotein CD5 is produced by our Mammalian expression system and the target gene encoding Gln24-Asn370 is expressed with a 6His tag at the C-terminus.
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Host	Human Cells
Accession Number	NP_031676.3
Endotoxin Level	< 1.0 EU per ?g as determined by the LAL method.
Mol Weight	38.9 kDa
Mw(kda)	38.9 kDa

Sequence Info	Gln24-Asn370

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by SDS-PAGE

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305466	PKSM041222	10ug	$117		Add to Cart
BHP10305466	PKSM041222	50ug	$297		Add to Cart

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