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Recombinant Mouse BAG family molecular chaperone regulator 3(Bag3)

BHP10502742
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Email
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Subcellular Location Nucleus, Cytoplasm
Uniprot Q9JLV1, Q9JLV1
Database Links

KEGG:mmu:29810

STRING:10090.ENSMUSP00000033136

UniGene:Mm.84073
Function Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti-apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport.
Research Area Others
Weight 63.7kDa
Stotage Note Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer Tris-based buffer，50% glycerol
Purity Greater than 90% as determined by SDS-PAGE.
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer Tris-based buffer,50% glycerol
Immunogen Species Mus Musculus (Mouse)
SKU Supplier No. Size Your price Quantity
BHP10502742 CSB-YP864372MO 500ug $1593
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BHP10502742 CSB-YP864372MO 100ug $576
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BHP10502742 CSB-YP864372MO 20ug $306
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