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Home / Proteins & Peptide

Recombinant Human TWF1/Twinfilin-1 Protein (His & GST Tag)

SKU : BHP10302855

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030992
Alternative Names	A6;MGC23788;MGC41876;PTK9
Reconstitution	Please refer to the printed manual for detailed information.
Background	Twinfilin-1; also known as Protein A6; Protein tyrosine kinase 9; TWF1 and PTK9; is a cytoplasm protein which belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highly conserved actin monomer-binding protein that regulates cytoskeletal dynamics in organisms from yeast to mammals. In addition to the mammalian twinfilin-1; a second protein with approximately 65% sequence identity to twinfilin-1 exists in mouse and humans. TWF1 / PTK9 is expressed at high levels in the colon; testis; ovary; prostate and lung. It is expressed at lower levels in the brain; bladder and heart. It is not detected in liver. TWF1 / PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization; likely by sequestering G-actin. By capping the barbed ends of filaments; it also regulates motility. TWF1 / PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.
Reactivity	Human
Tag	N-His & GST
Description	A DNA sequence encoding the human TWF1 isoform 4 (Q12792-4) (Met 1-Asp 252) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Formulation	Lyophilized from sterile 50mM Tris; 500mM NaCl; pH 8.0
Host	E.coli
Accession Number	Q12792-4
Endotoxin Level	Please contact us for more information.
Mol Weight	57 kDa
Mw(kda)	57 kDa

Sequence Info	Met 1-Asp 252

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 84 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302855	PKSH030992	100ug	$855		Add to Cart

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