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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human Tumor necrosis factor receptor superfamily member 17 protein (TNFRSF17), partial (Active)

BHP10500220
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Involvement In Disease A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Subcellular Location Cell membrane, Single-pass type III membrane protein, Endomembrane system, Single-pass type III membrane protein
Uniprot Q02223, Q02223
Database Links

HGNC:11913

OMIM:109545

KEGG:hsa:608

STRING:9606.ENSP00000053243

UniGene:Hs.2556
Function Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Research Area Cancer
Tissue Specificity Expressed in mature B-cells, but not in T-cells or monocytes.
Weight 5.4 kDa
Buffer 0.2 μm filtered 30 % acetonitrile, 0.1 % TFA,lyophilized
Purity >98% as determined by SDS-PAGE and HPLC.
Storage Buffer 0.2 μm filtered 30 % acetonitrile, 0.1 % TFA ,lyophilized
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10500220 CSB-AP002271HU 5ug $142
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BHP10500220 CSB-AP002271HU 100ug $2022
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BHP10500220 CSB-AP002271HU 500ug $4536
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