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Home / Proteins & Peptide

Recombinant Human TGF-beta 1

SKU : BHP15200005

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ELK Biotechnology

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Mfr.No.	EPT005
Alternative Names	Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB
Background	Transforming Growth Factor beta-1 (TGFbeta-1) is a secreted protein which belongs to the TGF-beta family. TGFbeta-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFbeta-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFbeta-1 peptide. TGFbeta-1 may also form heterodimers with other TGFbeta family members. It has been found that TGFbeta-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
Biological Activity	Measured by its ability to inhibit the IL-4-dependent proliferation of TF?1 human erythroleukemic cells. The ED50 for this effect is 4-40 pg/ml.
Description	Recombinant Human Transforming Growth Factor Beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.
Molecular Weight	12.8 KDa
Accession Number	P01137
Endotoxin Level	Less than 0.01 EU/ug as determined by LAL test.
Notes	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100ug/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Purity	Greater than 95%
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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SKU	Supplier No.	Size	Your price	Quantity
BHP15200005	EPT005	10ug	$279		Add to Cart

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