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Home / Proteins & Peptide

Recombinant Human SLAMF6/Ly108 Protein (aa 1-226, Fc Tag)

SKU : BHP10300483

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030962
Alternative Names	SLAMF6 ; KALI
Antigen	SLAMF6 / Ly108
Background	SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly108, is a single-pass type I membrane protein which belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6/ Ly108 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6/ Ly108 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6/ Ly108 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6/ Ly108 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6/ Ly108 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
Tag	Fc tag
Description	A DNA sequence encoding the human SLAMF6 (Q96DU3-1) (Met1-Met226) was expressed with the Fc region of human IgG1 at the C-terminus.
Regulatory	RUO
Host	Human Cells
Endotoxin Level	< 1.0 EU per μg of the protein as determined by the LAL method
Nature	Recombinant

Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Buffer	Lyophilized from sterile PBS, pH 7.4
Description	Please refer to the printed manual for detailed information.
Purity	(97.5+1.3) % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10300483	PKSH030962	100ug	$732		Add to Cart

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