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Home / Proteins & Peptide

Recombinant Human sCD23 (FCER2)

SKU : BHP10900270

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z101835
Alternative Names	Fc-epsilon-RII ; Immunoglobulin E-binding factor ; Lymphocyte IgE receptor ; CD23 ; B cell differentiation antigen ; Low affinity immunoglobulin epsilon Fc receptor ; BLAST-2
Description	CD23 is a calcium dependent transmembrane glycoprotein which is expressed in many cell types. The cytoplasmic region of the protein has two isoforms the 'a' isoform that participates in IgE-regulated endocytosis, and the 'b' isoform, which is involved in IgE-regulated phagocytosis. It has been found that there are at least four soluble forms of the CD23 protein (sCD23) all of which are produced by the activity of metallo/cysteine proteases. In addition to binding IgE, sCD23 have been shown to promote the activation and differentiation of B-cells and stimulate the release of pro-inflammatory cytokines from monocytes.
Quantity	20 µg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment	Measured by its ability to bind in a functional ELISA. Immobilized rhCD23 at 2 µg/mL (100 µL/well) can bind human IgE with a linear range of 0.0151 µg/mL.

Weight	19.5 kDa

Description	Reconstitute at 100 µg/mL in sterile PBS
Format	Lyophilized Powder Lyophilized from a 0.2 µm filtered solution in PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900270	Z101835	20µg	$214.44		Add to Cart

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