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Home / Proteins & Peptide

Recombinant Human p53 apoptosis effector related to PMP-22(PERP)

SKU : BHP10505924

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-CF839325HU
Description	Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway
Alternative Names	Keratinocyte-associated protein 1
Tag	N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Regulatory	RUO
Relevance	Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway
Source	in vitro E.coli expression system
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Keratinocyte-associated protein 1
Expression Region	1-193aa
Mol Weight	41.4kDa
Nature	Recombinant
Protein Description	Full Length

Subcellular Location	Cell junction, desmosome, Cell membrane, Multi-pass membrane protein
Uniprot	Q96FX8, Q96FX8
Database Links	HGNC:17637 OMIM:609301 KEGG:hsa:64065 STRING:9606.ENSP00000397157 UniGene:Hs.201446
Function	Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).
Pathway	p53 signaling pathway
Protein Families	TMEM47 family
Research Area	Cell Biology
Tissue Specificity	Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.
Weight	41.4 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505924	CSB-CF839325HU	100ug	$3216		Add to Cart
BHP10505924	CSB-CF839325HU	20ug	$1874		Add to Cart

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