p38ß is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress . The p38ß is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase . Alternatively spliced transcript variants encoding the same protein have been observed.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.