A DNA sequence encoding the human NUDT5 (Q9UKK9) (Glu2-Phe219) was expressed with a polyhistidine tag at the N-terminus.
Alternative Names
hYSAH1;YSA1;YSA1H;YSAH1
Reconstitution
Please refer to the printed manual for detailed information.
Background
ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites. NUDT5 functions as a MutT-related protein and catalyzes the hydrolysis of 8-oxoGDP to 8-oxoGMP, thereby preventing misincorporation of 8-oxoGua into RNA. NUDT5 may play significant roles in regulating the G1-S transition in mammalian cells. It can also hydrolyze other nucleotide sugars with low activity.
Reactivity
Human
Tag
N-His
Formulation
Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0
Host
E.coli
Accession Number
Q9UKK9
Endotoxin Level
Please contact us for more information.
Mol Weight
26.3 kDa
Mw(kda)
26.3 kDa
Sequence Info
Glu2-Phe219
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.