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Home / Proteins & Peptide

Recombinant Human NKG2DL/ULBP-1 Protein (Fc Tag)

SKU : BHP10303838

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH032815
Description	Recombinant Human UL16 Binding Protein-1/NKG2D ligand 1 is produced by our Mammalian expression system and the target gene encoding Gly26-Pro215 is expressed with a Fc tag at the C-terminus.
Alternative Names	NKG2D ligand 1;NKG2DL1;ALCAN-beta;Retinoic acid early transcript 1I;UL16-binding protein 1;ULBP1
Reconstitution	Please refer to the printed manual for detailed information.
Background	NKG2D ligand 1; also called ULBP1; is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC molecules possess alpha1; alpha2 and alpha3 domains; ULBP/RAET1 family members lack alpha3 domain. ULBP1 is recognized by the activating receptor NKG2D on the surface of cytotoxic natural killer (NK) and T cells; and then promotes the lysis of cells expressing ULBP1 which is important for the immune surveillance. ULBP1 and several other family members; ULBP2 and ULBP5; own the ability to bind the human cytomegalovirus (CMV) UL16 glycoprotein. The human CMV glycoprotein UL16 binds to intracellular ULBP1 and so inhibits its expression at the cell surface; which reduces the susceptibility of the virus-infected cell to cytotoxic destruction by NK cells. The expression of ULBP1 has been found on some tumor cells and is implicated in tumor surveillance.
Reactivity	Human
Tag	C-Fc
Formulation	Lyophilized from a 0.2 um filtered solution of PBS; pH7.4.
Host	Human Cells
Accession Number	Q9BZM6
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	49.4 kDa
Mw(kda)	49.4 kDa

Sequence Info	Gly26-Pro215

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303838	PKSH032815	10ug	$117		Add to Cart
BHP10303838	PKSH032815	50ug	$297		Add to Cart

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