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Home / Proteins & Peptide

Recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 Protein (Fc Tag)(Active)

SKU : BHP10303108

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031985
Alternative Names	BDA2;BDA2A;BMP-2;BMP2A;BMP2
Reconstitution	Please refer to the printed manual for detailed information.
Background	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
Reactivity	Human
Tag	C-Fc
Description	A DNA sequence encoding the mature form of human BMP2 (NP_001191.1) (Gln 283-Arg 396) was fused with the Fc region of human IgG1 at the C-terminus. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.
Formulation	Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5. 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. 2. Please contact us for any concerns or special requirements.
Host	HEK293 Cells
Accession Number	NP_001191.1
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Bioactivity	1.Measured by its ability to bind recombinant human Nog-Fc in a functional ELISA.2. Measured by its ability to bind recombinant human ALK3-Fch in a functional ELISA.3. Measured by its ability to bind recombinant mouse ALK3-Fch in a functional ELISA.4. Measured by its ability to bind recombinant human BMPR-II-Fc in a functional ELISA.
Mol Weight	39.5 kDa
Mw(kda)	39.5 kDa

Sequence Info	Gln 283-Arg 396

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303108	PKSH031985	20ug	$366		Add to Cart
BHP10303108	PKSH031985	100ug	$921		Add to Cart

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